JPH0235740B2 - - Google Patents

Info

Publication number
JPH0235740B2
JPH0235740B2 JP58026559A JP2655983A JPH0235740B2 JP H0235740 B2 JPH0235740 B2 JP H0235740B2 JP 58026559 A JP58026559 A JP 58026559A JP 2655983 A JP2655983 A JP 2655983A JP H0235740 B2 JPH0235740 B2 JP H0235740B2
Authority
JP
Japan
Prior art keywords
formula
group
general formula
biphenylyl
fluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58026559A
Other languages
English (en)
Japanese (ja)
Other versions
JPS59152348A (ja
Inventor
Katsuhiro Uchida
Shozo Masumoto
Masao Tono
Mitsuo Mimura
Makoto Okumura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kaken Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaken Pharmaceutical Co Ltd filed Critical Kaken Pharmaceutical Co Ltd
Priority to JP58026559A priority Critical patent/JPS59152348A/ja
Priority to AU18772/83A priority patent/AU559633B2/en
Priority to AT83108796T priority patent/ATE23988T1/de
Priority to CA000436223A priority patent/CA1240333A/en
Priority to EP19830108796 priority patent/EP0103265B1/en
Priority to NZ20551683A priority patent/NZ205516A/en
Priority to DE8383108796T priority patent/DE3368046D1/de
Priority to ES525498A priority patent/ES8502962A1/es
Publication of JPS59152348A publication Critical patent/JPS59152348A/ja
Priority to US06/742,147 priority patent/US4766148A/en
Priority to US07/204,313 priority patent/US5196567A/en
Publication of JPH0235740B2 publication Critical patent/JPH0235740B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
JP58026559A 1982-09-10 1983-02-19 ビフエニリルプロピオン酸エステル誘導体およびその製造法 Granted JPS59152348A (ja)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP58026559A JPS59152348A (ja) 1983-02-19 1983-02-19 ビフエニリルプロピオン酸エステル誘導体およびその製造法
AU18772/83A AU559633B2 (en) 1982-09-10 1983-09-06 Biphenylyl propionic acid derivatives
NZ20551683A NZ205516A (en) 1982-09-10 1983-09-07 Biphenylpropionic acid derivatives and pharmaceutical compositions
CA000436223A CA1240333A (en) 1983-02-19 1983-09-07 Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same
EP19830108796 EP0103265B1 (en) 1982-09-10 1983-09-07 Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same
AT83108796T ATE23988T1 (de) 1982-09-10 1983-09-07 Derivat der biphenylpropionsaeure, herstellungsverfahren und dieses enthaltende pharmazeutische komposition.
DE8383108796T DE3368046D1 (en) 1982-09-10 1983-09-07 Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same
ES525498A ES8502962A1 (es) 1982-09-10 1983-09-08 Un procedimiento para preparar un derivado de acido bifenililpropionico
US06/742,147 US4766148A (en) 1983-02-19 1985-06-07 Biphenylylpropionic acid derivative and pharmaceutical composition containing the same
US07/204,313 US5196567A (en) 1983-02-19 1988-06-09 Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58026559A JPS59152348A (ja) 1983-02-19 1983-02-19 ビフエニリルプロピオン酸エステル誘導体およびその製造法

Publications (2)

Publication Number Publication Date
JPS59152348A JPS59152348A (ja) 1984-08-31
JPH0235740B2 true JPH0235740B2 (en]) 1990-08-13

Family

ID=12196885

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58026559A Granted JPS59152348A (ja) 1982-09-10 1983-02-19 ビフエニリルプロピオン酸エステル誘導体およびその製造法

Country Status (3)

Country Link
US (1) US4766148A (en])
JP (1) JPS59152348A (en])
CA (1) CA1240333A (en])

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0477935U (en]) * 1990-11-16 1992-07-07

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108456140B (zh) * 2018-03-06 2021-06-11 心邀（深圳）生物科技有限公司 一种制备氟比洛芬杂质m的方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2518922A (en) * 1946-06-19 1950-08-15 Monsanto Chemicals Salicylic acid derivatives and method for making same
GB1091403A (en) * 1964-01-24 1967-11-15 Boots Pure Drug Co Ltd Therapeutically active phenylalkane derivatives
GB1345628A (en) * 1970-04-07 1974-01-30 Merck & Co Inc Indenyl acetates
GB1359987A (en) * 1970-10-12 1974-07-17 Boots Co Ltd 2-substituted biphenylyl propionic acids
US3752844A (en) * 1971-10-01 1973-08-14 Merck & Co Inc Esters of indenyl alkanoic acids
GB1576841A (en) * 1977-01-22 1980-10-15 Beecham Group Ltd Substituted n-acyl phenylamine compounds having hypolipidaemic activity
US4256760A (en) * 1979-01-09 1981-03-17 Laboratorios Bago S.A. Methods of treating mammals suffering from inflammation and pain
DE2914789A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Injizierbare arzneimittel mit entzuendungshemmender wirkung
JPS6030652B2 (ja) * 1979-05-07 1985-07-17 株式会社ミドリ十字 静脈注射用脂肪乳剤
CA1173360A (en) * 1979-06-22 1984-08-28 Jurg Schrank Pharmaceutical preparations
JPS5645467A (en) * 1979-09-20 1981-04-25 Nippon Chemiphar Co Ltd Pantolactone derivative and its preparation
DE2948607A1 (de) * 1979-12-03 1981-06-11 Chemische Fabrik Dr. Meyer-Castens & Co Nfg., 2000 Hamburg Verfahren zur herstellung eines emulgators auf lecithinbasis
US4266069A (en) * 1979-12-19 1981-05-05 The Upjohn Company Processes for the preparation of hydratropic acids and esters
US4398035A (en) * 1979-12-19 1983-08-09 The Upjohn Company Malonic acids and esters thereof
US4324904A (en) * 1979-12-19 1982-04-13 The Upjohn Company Processes for the preparation of hydratropic acids and esters
EP0032620B2 (en) * 1979-12-19 1987-02-04 The Upjohn Company Process for preparing therapeutic 2-arylpropionic acids and esters, and novel arylmethylmalonate esters
JPS609726B2 (ja) * 1980-05-15 1985-03-12 株式会社 ミドリ十字 ステロイド製剤
JPS5924132B2 (ja) * 1980-12-02 1984-06-07 株式会社 林原生物化学研究所 栄養補給用乳剤の製法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0477935U (en]) * 1990-11-16 1992-07-07

Also Published As

Publication number Publication date
US4766148A (en) 1988-08-23
CA1240333A (en) 1988-08-09
JPS59152348A (ja) 1984-08-31

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